Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | SNCA | P37840 | 1/20 | 0.64 |
| ▸ | TYR | P14679 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28717631 | 0.90 | TYR (0.61) | ACHEPTGS1SNCATYRCA12 | |
| SCHEMBL19386144 | 0.87 | SNCA (0.62) | ACHEPTGS1SNCATYREPHX2 | |
| SCHEMBL20873819 | 0.87 | SNCA (0.62) | ACHEPTGS1SNCATYREPHX2 | |
| SCHEMBL29498360 | 0.86 | ACHE (0.74) | ACHEPTGS1SNCATYREPHX2 | |
| SCHEMBL15394681 | 0.86 | ACHE (0.74) | ACHEPTGS1SNCATYREPHX2 | |
| SCHEMBL13576882 | 0.86 | ACHE (0.74) | ACHEPTGS1SNCATYREPHX2 | |
| SCHEMBL29360789 | 0.86 | ACHE (0.70) | ACHEPTGS1SNCATYRKDM4E | |
| SCHEMBL5597588 | 0.86 | ACHE (0.70) | ACHEPTGS1SNCATYRKDM4E | |
| SCHEMBL3353611 | 0.86 | ACHE (0.70) | ACHEPTGS1SNCATYRKDM4E | |
| SCHEMBL13577077 | 0.86 | ACHE (0.74) | ACHEPTGS1SNCATYREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |