Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK1 | P19367 | 1/20 | 0.46 |
| ▸ | HK2 | P52789 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14119799 | 0.91 | TYR (0.55) | TYR | |
| SCHEMBL20056340 | 0.91 | TYR (0.55) | TYR | |
| SCHEMBL16027274 | 0.87 | HK1 (0.51) | HK1HK2 | |
| SCHEMBL16027276 | 0.87 | HK1 (0.51) | HK1HK2 | |
| SCHEMBL16027490 | 0.82 | TYR (0.48) | TYR | |
| SCHEMBL16027488 | 0.82 | TYR (0.48) | TYR | |
| SCHEMBL12476682 | 0.81 | TYR (0.56) | HK1HK2TYR | |
| SCHEMBL12476686 | 0.81 | TYR (0.56) | HK1HK2TYR | |
| SCHEMBL14120235 | 0.81 | TYR (0.56) | HK1HK2TYR | |
| SCHEMBL16027267 | 0.80 | HK1 (0.48) | HK1HK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |