Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13034261 | 0.90 | KLK7 (0.46) | KLK7FKBP1AOPRD1MEN1KMT2A | |
| SCHEMBL2689602 | 0.90 | KLK7 (0.49) | KLK7FKBP1AOPRD1MEN1KMT2A | |
| SCHEMBL3046705 | 0.90 | KLK7 (0.49) | KLK7FKBP1AOPRD1MEN1KMT2A | |
| SCHEMBL13086596 | 0.90 | KLK7 (0.49) | KLK7FKBP1AOPRD1MEN1KMT2A | |
| SCHEMBL13086758 | 0.87 | MEN1 (0.50) | KLK7FKBP1AOPRD1MEN1KMT2A | |
| SCHEMBL13086595 | 0.86 | MEN1 (0.49) | KLK7FKBP1AOPRD1MEN1KMT2A | |
| SCHEMBL13086597 | 0.85 | MEN1 (0.48) | KLK7FKBP1AOPRD1MEN1KMT2A | |
| SCHEMBL6012084 | 0.85 | MEN1 (0.48) | KLK7FKBP1AOPRD1MEN1KMT2A | |
| SCHEMBL13086353 | 0.85 | MEN1 (0.48) | KLK7FKBP1AOPRD1MEN1KMT2A | |
| SCHEMBL7528184 | 0.85 | FKBP1A (0.48) | KLK7FKBP1AOPRD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883627-B1 | BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2018-04-18 | — | — | EP | disclosed |