Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258055 | 0.78 | EPHX1 (0.52) | ALDH1A1KDM4ELMNAHTTMAOA | |
| SCHEMBL1327511 | 0.75 | HTT (0.56) | ALDH1A1KDM4ELMNAHTTMAOA | |
| SCHEMBL8249322 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAHTTMAOA | |
| SCHEMBL1327514 | 0.75 | HTT (0.56) | ALDH1A1KDM4ELMNAHTTMAOA | |
| SCHEMBL14930299 | 0.75 | HTT (0.56) | ALDH1A1KDM4ELMNAHTTMAOA | |
| SCHEMBL13694093 | 0.74 | GRIN2B (0.47) | KDM1ALMNAHTR6 | |
| SCHEMBL18995758 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAHTTMAOA | |
| SCHEMBL7331088 | 0.74 | EPHX2 (0.60) | ALDH1A1KDM4EHTT | |
| SCHEMBL6254978 | 0.74 | EPHX2 (0.60) | ALDH1A1KDM4EHTT | |
| SCHEMBL6252685 | 0.73 | KDM4E (0.65) | ALDH1A1KDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883627-B1 | BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2018-04-18 | — | — | EP | disclosed |