Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21302048 | 0.98 | DNM1 (0.50) | DNM1GGPS1SPHK1TSHRTHRB | |
| SCHEMBL21302042 | 0.98 | DNM1 (0.50) | DNM1GGPS1SPHK1TSHRTHRB | |
| SCHEMBL23695909 | 0.98 | DNM1 (0.50) | DNM1GGPS1SPHK1TSHRTHRB | |
| SCHEMBL22433449 | 0.98 | DNM1 (0.50) | DNM1GGPS1SPHK1TSHRTHRB | |
| SCHEMBL21960098 | 0.92 | DNM1 (0.36) | DNM1SPHK1TSHR | |
| SCHEMBL13417326 | 0.92 | DNM1 (0.36) | DNM1SPHK1TSHR | |
| SCHEMBL13417325 | 0.81 | — | — | |
| SCHEMBL13788715 | 0.81 | DNM1 (0.42) | DNM1GGPS1SPHK1OPRM1 | |
| SCHEMBL10953399 | 0.79 | DNM1 (0.50) | DNM1GGPS1OPRM1TSHRTHRB | |
| SCHEMBL21449244 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883627-B1 | BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2018-04-18 | — | — | EP | disclosed |