SCHEMBL2005718

SCHEMBL2005718

BrC1CNCCNCCN1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.35
MAPT P10636 1/20 0.35
PDE4A P27815 1/20 0.35
KDR P35968 1/20 0.35
CXCR4 P61073 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4328952 0.97
SCHEMBL8200668 0.67 HIF1A (0.38) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL17344128 0.67 HIF1A (0.38) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL8192639 0.67 HIF1A (0.38) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL8200112 0.67 HIF1A (0.38) HIF1AMAPTPDE4AKDRCXCR4
Piperazine SCHEMBL7612531 0.67 HIF1A (0.38) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL30485151 0.67
SCHEMBL18679 0.67 HIF1A (0.38) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL9172235 0.67 HIF1A (0.38) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL8192635 0.67 HIF1A (0.38) HIF1AMAPTPDE4AKDRCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1857471-B1 POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER MITSUI CHEMICALS INC (JP) 2013-04-24 EP disclosed
US-7960305-B2 a mixture of a phosphazenium compound such as tetrakis[tris(dimethylamino)phosphoranylideneamino]phosphonium chloride, transition metal halides and an organic halogen compound as an activator, used for addition homo/copolymerization; living polymers MITSUI CHEMICALS, INC. (JP) 2011-06-14 US disclosed
US-20080177014-A1 Polymerization Catalyst Composition and Process for Production of Polymer MITSUI CHEMICALS, INC. (JP) 2008-07-24 US disclosed
EP-1857471-A1 POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER Mitsui Chemicals, Inc. (JP) 2007-11-21 EP disclosed