Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047674 | 0.89 | KMT2A (0.76) | CYP1A2KMT2AALDH1A1TP53TYR | |
| SCHEMBL29654057 | 0.81 | ALDH1A1 (0.62) | CYP1A2KMT2AALDH1A1TP53TYR | |
| SCHEMBL5459330 | 0.81 | ALDH1A1 (0.62) | CYP1A2KMT2AALDH1A1TP53TYR | |
| SCHEMBL20714982 | 0.80 | CYP1A2 (0.43) | CYP1A2KMT2AALDH1A1TSHRHSD17B10 | |
| SCHEMBL1886408 | 0.80 | CYP1A2 (1.00) | CYP1A2KMT2AALDH1A1TP53TYR | |
| SCHEMBL8350546 | 0.80 | GAA (0.50) | CYP1A2ALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL11751583 | 0.79 | ALDH1A1 (0.61) | CYP1A2KMT2AALDH1A1TP53TYR | |
| SCHEMBL29654010 | 0.78 | KMT2A (0.66) | CYP1A2KMT2AALDH1A1TP53TYR | |
| SCHEMBL28936790 | 0.78 | KMT2A (0.66) | CYP1A2KMT2AALDH1A1TP53TYR | |
| SCHEMBL1884582 | 0.78 | KMT2A (1.00) | CYP1A2KMT2AALDH1A1TP53TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309146-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2018-04-18 | — | — | EP | disclosed |