SCHEMBL20057546

SCHEMBL20057546

NC(=O)C1=C(O)NCC=N1

nearest known ligand 0.31

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.31
TSHR P16473 1/20 0.31
MC4R P32245 1/20 0.31
ADRA1A P35348 1/20 0.31
MC3R P41968 1/20 0.31
CDC7 O00311 1/20 0.31
DBF4 Q9UBU7 1/20 0.31
NNMT P40261 1/20 0.31
MAPK8 P45983 1/20 0.30
CSNK1A1 P48729 1/20 0.30
LIMK1 P53667 1/20 0.30
MAP2K1 Q02750 1/20 0.30
PRKAA1 Q13131 1/20 0.30
DYRK1A Q13627 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30
DYRK1B Q9Y463 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7854217 0.72
SCHEMBL15759491 0.64 CSNK1A1 (0.33) CSNK1A1
SCHEMBL17375241 0.61
SCHEMBL184925 0.58
SCHEMBL8689309 0.55
SCHEMBL8777769 0.55
SCHEMBL15088557 0.54
SCHEMBL5272284 0.53
SCHEMBL17956810 0.53
SCHEMBL2145978 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3309149-A1 6-BROMO-3-HYDROXY-2-PYRAZINECARBOXAMIDE CRYSTAL AND METHOD FOR PRODUCING SAME Toyama Chemical Co., Ltd. (JP) 2018-04-18 EP disclosed