⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13356562 | 0.79 | — | — | |
| SCHEMBL7854217 | 0.65 | — | — | |
| SCHEMBL2365680 | 0.65 | — | — | |
| SCHEMBL7410738 | 0.62 | — | — | |
| SCHEMBL30092668 | 0.61 | — | — | |
| SCHEMBL20057546 | 0.61 | ADORA3 (0.31) | — | |
| SCHEMBL18120590 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL30701021 | 0.60 | — | — | |
| SCHEMBL16054720 | 0.60 | — | — | |
| SCHEMBL15320514 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260007672-A1 | INHIBITORS OF MPTP | NRG THERAPEUTICS LTD (GB) | 2026-01-08 | — | — | US | disclosed |
| EP-4652162-A1 | INHIBITORS OF MPTP | NRG Therapeutics LTD (GB) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153946-A1 | INHIBITORS OF MPTP | NRG THERAPEUTICS LTD (GB) | 2024-07-25 | — | — | WO | disclosed |
| CN-112969704-A | Urea 6, 7-dihydro-4H-pyrazolo [1,5-a ] pyrazine active agents against hepatitis b virus HBV | 艾库里斯有限及两合公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-110183449-A | Mnk inhibitors and methods related thereto | 效应治疗股份有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-106795162-B | Mnk inhibitors and methods related thereto | 效应治疗股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-106795162-A | Mnk inhibitors and methods related thereto | 效应治疗股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-3160966-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | Effector Therapeutics Inc. (US) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015200481-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS, INC. (US) | 2015-12-30 | — | — | WO | disclosed |