Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019393 | 0.92 | TP53 (0.69) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL30888839 | 0.82 | TP53 (0.58) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL8153658 | 0.81 | HSD17B10 (0.65) | TP53PNPLA2HDAC6APEX1 | |
| SCHEMBL10425058 | 0.81 | ALDH1A1 (0.65) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL11164480 | 0.81 | TP53 (0.61) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL10705800 | 0.81 | TP53 (0.56) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL11862075 | 0.81 | POLB (0.68) | TP53PNPLA2HDAC6 | |
| SCHEMBL11878225 | 0.81 | NPSR1 (0.61) | TP53PNPLA2HDAC6APEX1KDM4E | |
| SCHEMBL23169533 | 0.80 | TP53 (0.64) | TP53PNPLA2HDAC6APEX1TSHR | |
| SCHEMBL10808693 | 0.80 | TP53 (0.59) | TP53PNPLA2HDAC6APEX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309146-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | University of Tsukuba (JP) | 2018-04-18 | — | — | EP | disclosed |