Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115564 | 0.87 | XDH (0.57) | XDHS1PR1S1PR3S1PR5 | |
| SCHEMBL2115714 | 0.86 | XDH (0.56) | XDHS1PR1S1PR3S1PR5 | |
| SCHEMBL2122849 | 0.84 | XDH (0.54) | XDHS1PR1S1PR3S1PR5 | |
| SCHEMBL20058181 | 0.81 | XDH (0.58) | XDHS1PR1S1PR5 | |
| SCHEMBL4366155 | 0.81 | S1PR1 (0.66) | XDHS1PR1S1PR5 | |
| SCHEMBL2602067 | 0.81 | S1PR1 (0.66) | XDHS1PR1S1PR3S1PR5 | |
| SCHEMBL21300280 | 0.80 | S1PR1 (0.62) | XDHS1PR1S1PR5 | |
| Hydrochloric Acid SCHEMBL2115459 | 0.80 | S1PR1 (0.65) | XDHS1PR1S1PR3S1PR5 | |
| SCHEMBL2117220 | 0.79 | S1PR1 (0.67) | XDHS1PR1S1PR3S1PR5 | |
| SCHEMBL18360175 | 0.78 | S1PR1 (0.55) | XDHS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498609-B1 | SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2018-04-18 | — | — | EP | disclosed |