Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667075 | 0.84 | S1PR1 (0.54) | S1PR1 | |
| SCHEMBL19507973 | 0.84 | S1PR1 (0.54) | S1PR1 | |
| SCHEMBL20057746 | 0.84 | S1PR1 (0.54) | S1PR1 | |
| SCHEMBL13974393 | 0.84 | XDH (0.38) | S1PR1CYP11B2 | |
| SCHEMBL20058078 | 0.83 | S1PR1 (0.41) | S1PR1CYP11B2 | |
| SCHEMBL19507690 | 0.83 | S1PR1 (0.39) | S1PR1CYP11B2 | |
| SCHEMBL13974230 | 0.82 | S1PR1 (0.56) | S1PR1 | |
| SCHEMBL17192144 | 0.81 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL17192143 | 0.81 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL21300299 | 0.76 | S1PR1 (0.46) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498609-B1 | SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2018-04-18 | — | — | EP | disclosed |