Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KCNB1 | Q14721 | 2/20 | 0.42 |
| ▸ | KCNB2 | Q92953 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15836549 | 0.81 | KCNB1 (0.36) | SMN1; SMN2MAPTKCNB1KCNB2BACE1 | |
| SCHEMBL10985268 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL21440768 | 0.75 | KCNB1 (0.33) | MAPTKCNB1KCNB2BACE1BACE2 | |
| SCHEMBL29793691 | 0.72 | MAPT (0.46) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL14048151 | 0.72 | ALDH1A1 (0.42) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL15490163 | 0.72 | MAPT (0.46) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL12505382 | 0.70 | GAA (0.54) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL31565670 | 0.70 | IKBKB (0.49) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL15486878 | 0.70 | MAPT (0.44) | SMN1; SMN2MAPTMEN1KMT2AHPGD | |
| SCHEMBL2092186 | 0.70 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309549-A1 | RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS | Waters Technologies Corporation (US) | 2018-04-18 | — | — | EP | disclosed |