Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16304051 | 1.00 | P2RX4 (0.52) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 | |
| SCHEMBL18844897 | 0.89 | P2RX4 (0.50) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 | |
| SCHEMBL9421329 | 0.88 | P2RX4 (0.54) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 | |
| SCHEMBL15514849 | 0.87 | P2RX4 (0.56) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 | |
| SCHEMBL16306625 | 0.87 | P2RX4 (0.56) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 | |
| SCHEMBL18596699 | 0.84 | MAPT (0.54) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 | |
| SCHEMBL14259581 | 0.83 | P2RX4 (0.55) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 | |
| SCHEMBL10028312 | 0.83 | P2RX4 (0.55) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 | |
| SCHEMBL1623512 | 0.83 | P2RX4 (0.55) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 | |
| SCHEMBL16158123 | 0.83 | P2RX4 (0.55) | P2RX4ALDH1A1CYP19A1LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793883-B1 | TRPM8 ANTAGONISTS | DOMPE FARM SPA (IT) | 2018-04-18 | — | — | EP | disclosed |