Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20058327 | 0.92 | KDM4E (0.36) | AKR1C4AKR1C3AKR1C2AKR1C1PTGER4 | |
| SCHEMBL13872357 | 0.91 | KDM4E (0.38) | AKR1C4AKR1C3AKR1C2AKR1C1PTGER4 | |
| SCHEMBL20058326 | 0.88 | KDM4E (0.35) | AKR1C4AKR1C3AKR1C2AKR1C1PTGER4 | |
| SCHEMBL13872338 | 0.86 | KDM4E (0.38) | AKR1C4AKR1C3AKR1C2AKR1C1PTGER4 | |
| SCHEMBL9920734 | 0.86 | KDM4E (0.38) | AKR1C4AKR1C3AKR1C2AKR1C1PTGER4 | |
| SCHEMBL12612080 | 0.86 | NLRP3 (0.37) | KDM4EATML3MBTL1POLBLMNA | |
| SCHEMBL20107148 | 0.86 | AKR1C4 (0.35) | AKR1C4AKR1C3AKR1C2AKR1C1PTGER4 | |
| SCHEMBL20107145 | 0.85 | MAPKAPK2 (0.36) | POLBMAPTTP53 | |
| SCHEMBL20058306 | 0.85 | KDM4E (0.37) | AKR1C4AKR1C3AKR1C2AKR1C1PTGER4 | |
| SCHEMBL13872311 | 0.85 | KDM4E (0.39) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942171-B1 | LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE | TORAY INDUSTRIES (JP) | 2018-04-18 | — | — | EP | disclosed |