Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24767308 | 0.84 | ALDH1A1 (0.36) | PTPRB | |
| SCHEMBL21699632 | 0.84 | PTPRB (0.54) | PTPRBPTPN1 | |
| SCHEMBL20060084 | 0.84 | PTPRB (0.54) | PTPRBPTPN1 | |
| SCHEMBL20059864 | 0.83 | PTPRB (0.56) | PTPRBPTPN1 | |
| SCHEMBL19775508 | 0.81 | PTPRB (0.77) | PTPRB | |
| SCHEMBL28828143 | 0.81 | PTPRB (0.54) | PTPRBPTPN1 | |
| SCHEMBL19775200 | 0.81 | PTPRB (0.75) | PTPRB | |
| SCHEMBL28828147 | 0.81 | PTPRB (0.57) | PTPRBPTPN1 | |
| SCHEMBL19775219 | 0.80 | PTPRB (0.77) | PTPRB | |
| SCHEMBL20787811 | 0.80 | PTPRB (0.56) | PTPRBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607821-A1 | COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES | Aerpio Therapeutics, Inc. (US) | 2020-02-12 | — | — | EP | disclosed |
| EP-2967066-B1 | COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES | AERPIO THERAPEUTICS INC (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-2451279-B1 | BENZOSULFONAMIDE DERIVATIVES, COMPOSITIONS THEREOF, AND THEIR USE IN PREVENTING METASTASIS OF CANCER CELLS | AERPIO THERAPEUTICS INC (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-2385763-B1 | METHODS FOR TREATING VASCULAR LEAK SYNDROME | AERPIO THERAPEUTICS INC (US) | 2018-04-18 | — | — | EP | disclosed |