Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18871452 | 0.85 | TP53 (0.42) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL20059936 | 0.79 | TP53 (0.33) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL20059894 | 0.77 | TP53 (0.35) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL20060158 | 0.73 | TP53 (0.39) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL7547316 | 0.67 | — | — | |
| SCHEMBL14654099 | 0.66 | — | — | |
| SCHEMBL20060150 | 0.65 | KDM4E (0.31) | — | |
| SCHEMBL14135604 | 0.64 | — | — | |
| SCHEMBL18871426 | 0.63 | SMN1; SMN2 (0.46) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL4561152 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |