Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20059894 | 0.86 | TP53 (0.35) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL20060146 | 0.79 | TP53 (0.36) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL20060158 | 0.79 | TP53 (0.39) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL14654166 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL22056814 | 0.69 | ADH1B (0.42) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL20060210 | 0.68 | — | — | |
| SCHEMBL29581778 | 0.64 | L3MBTL1 (0.44) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL7547316 | 0.63 | — | — | |
| SCHEMBL18871452 | 0.63 | TP53 (0.42) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL20060159 | 0.63 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |