Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13849416 | 0.99 | KDM4E (0.59) | KDM4ETDP1LTA4HSMN1; SMN2HTT | |
| SCHEMBL1911862 | 0.90 | MEN1 (0.53) | KDM4ELTA4HSMN1; SMN2ALDH1A1 | |
| SCHEMBL1911850 | 0.87 | NPC1 (0.66) | KDM4ESMN1; SMN2POLBALDH1A1 | |
| SCHEMBL13849370 | 0.87 | SMN1; SMN2 (0.63) | KDM4ELTA4HSMN1; SMN2HTTPOLB | |
| SCHEMBL12961350 | 0.86 | DRD3 (0.47) | KDM4ETDP1LTA4HSMN1; SMN2HTT | |
| SCHEMBL13849419 | 0.85 | KDM4E (0.51) | KDM4ESMN1; SMN2HTTMAOB | |
| SCHEMBL13849420 | 0.85 | MAOB (0.50) | KDM4ELTA4HALDH1A1MAOBESR1 | |
| SCHEMBL13091445 | 0.84 | KDM4E (0.71) | KDM4ELTA4HSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL1964263 | 0.84 | LTA4H (0.59) | KDM4ELTA4HSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1962645 | 0.83 | LTA4H (0.58) | KDM4ELTA4HPOLBPSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |