SCHEMBL20060481

SCHEMBL20060481

C=CC(=O)OCC(C)C(F)(F)C(C)(C)COC(=O)C=C

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.51
ALDH1A1 P00352 4/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22624515 0.91 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL20114092 0.89 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL20787717 0.83 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL18505874 0.83 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL20374260 0.83 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL15304441 0.82 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21204968 0.81 ALDH1A1 (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL20015418 0.80 TSHR (0.62) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29679599 0.79 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29679915 0.78 TSHR (0.51) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11112599-B2 Antireflection film having hard coating layer and display device including the same LG CHEM, LTD. (KR) 2021-09-07 US disclosed
EP-2749915-B1 METHOD FOR MANUFACTURING ANTI-GLARE FILM LG CHEMICAL LTD (KR) 2019-07-31 EP disclosed
US-20180223113-A1 ANTIREFLECTION FILM AND DISPLAY DEVICE XINMEI FONTANA HOLDING (HONG KONG) LIMITED (CN) 2018-08-09 US disclosed
EP-3309222-A1 PHOTOCURABLE COATING COMPOSITION, LOW-REFRACTION LAYER, AND ANTI-REFLECTION FILM LG Chem, Ltd. (KR) 2018-04-18 EP disclosed