Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.78 |
| ▸ | MAPK12 | P53778 | 15/20 | 0.78 |
| ▸ | HCK | P08631 | 13/20 | 0.78 |
| ▸ | SRC | P12931 | 7/20 | 0.78 |
| ▸ | GSK3A | P49840 | 4/20 | 0.78 |
| ▸ | SYK | P43405 | 4/20 | 0.78 |
| ▸ | GSK3B | P49841 | 1/20 | 0.78 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14701833 | 0.96 | MAPK14 (0.85) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL12542400 | 0.92 | MAPK12 (0.92) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL20060669 | 0.90 | MAPK12 (0.66) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL20386609 | 0.89 | MAPK14 (0.84) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL1292838 | 0.88 | SRC (0.83) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL20060634 | 0.88 | MAPK14 (0.67) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL20060620 | 0.88 | MAPK14 (0.67) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL1292878 | 0.88 | MAPK14 (0.84) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL2531614 | 0.88 | MAPK12 (1.00) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL20060710 | 0.87 | MAPK14 (0.81) | MAPK14MAPK12HCKSRCGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582433-B1 | UREIDO-PYRAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF RHINOVIRUS INFECTIONS | RESPIVERT LTD (GB) | 2018-04-18 | — | — | EP | disclosed |