Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.65 |
| ▸ | SRC | P12931 | 13/20 | 0.65 |
| ▸ | SYK | P43405 | 13/20 | 0.65 |
| ▸ | GSK3A | P49840 | 13/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.59 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.59 |
| ▸ | HCK | P08631 | 3/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | CIT | O14578 | 1/20 | 0.58 |
| ▸ | MUSK | O15146 | 1/20 | 0.58 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.58 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.58 |
| ▸ | STK10 | O94804 | 1/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.58 |
| ▸ | RAF1 | P04049 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12541122 | 0.93 | MAPK14 (0.75) | MAPK14SRCSYKGSK3AMAPK12 | |
| SCHEMBL1292752 | 0.89 | MAPK14 (0.78) | MAPK14SRCSYKGSK3AMAPK12 | |
| SCHEMBL20060614 | 0.89 | MAPK14 (0.62) | MAPK14SRCSYKGSK3AMAPK12 | |
| SCHEMBL20060620 | 0.88 | MAPK14 (0.67) | MAPK14SRCSYKGSK3AMAPK12 | |
| SCHEMBL20060609 | 0.87 | MAPK14 (0.63) | MAPK14SRCSYKGSK3AMAPK12 | |
| SCHEMBL20060700 | 0.87 | MAPK14 (0.64) | MAPK14SRCSYKGSK3AMAPK12 | |
| SCHEMBL20060634 | 0.87 | MAPK14 (0.67) | MAPK14SRCSYKGSK3AMAPK12 | |
| SCHEMBL1292745 | 0.85 | MAPK14 (0.72) | MAPK14SRCSYKGSK3AMAPK12 | |
| SCHEMBL20060625 | 0.84 | MAPK14 (0.62) | MAPK14SRCSYKGSK3AMAPK12 | |
| SCHEMBL20060611 | 0.84 | MAPK14 (0.62) | MAPK14SRCSYKGSK3AMAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582433-B1 | UREIDO-PYRAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF RHINOVIRUS INFECTIONS | RESPIVERT LTD (GB) | 2018-04-18 | — | — | EP | disclosed |