Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.62 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.62 |
| ▸ | SRC | P12931 | 10/20 | 0.61 |
| ▸ | GSK3A | P49840 | 8/20 | 0.61 |
| ▸ | HCK | P08631 | 8/20 | 0.61 |
| ▸ | SYK | P43405 | 7/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529985 | 0.93 | MAPK14 (0.74) | MAPK14MAPK12SRCGSK3AHCK | |
| SCHEMBL20060614 | 0.93 | MAPK14 (0.62) | MAPK14MAPK12SRCGSK3AHCK | |
| SCHEMBL20060634 | 0.87 | MAPK14 (0.67) | MAPK14MAPK12SRCGSK3AHCK | |
| SCHEMBL12540837 | 0.87 | MAPK14 (0.76) | MAPK14MAPK12SRCGSK3AHCK | |
| SCHEMBL20060697 | 0.87 | MAPK14 (0.65) | MAPK14MAPK12SRCGSK3AHCK | |
| SCHEMBL20060583 | 0.87 | MAPK14 (0.68) | MAPK14MAPK12SRCGSK3AHCK | |
| SCHEMBL2533270 | 0.86 | MAPK14 (0.73) | MAPK14MAPK12SRCGSK3AHCK | |
| SCHEMBL20060606 | 0.85 | MAPK14 (0.59) | MAPK14MAPK12SRCGSK3AHCK | |
| SCHEMBL20060665 | 0.84 | MAPK14 (0.65) | MAPK14MAPK12SRCGSK3AHCK | |
| SCHEMBL20060620 | 0.84 | MAPK14 (0.67) | MAPK14MAPK12SRCGSK3AHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582433-B1 | UREIDO-PYRAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF RHINOVIRUS INFECTIONS | RESPIVERT LTD (GB) | 2018-04-18 | — | — | EP | disclosed |