SCHEMBL20060789

SCHEMBL20060789

c1ccc(-c2nc(-c3ccnc(-n4c5ccccc5c5cc6c7ccccc7n(-c7ccccc7)c6cc54)c3)nc(-c3cccc4ccccc34)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
ATM Q13315 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 4/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
MAPK1 P28482 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
HSD17B10 Q99714 3/20 0.34
TP53 P04637 2/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PDE4A P27815 2/20 0.33
PDE4B Q07343 2/20 0.33
PDE4C Q08493 2/20 0.33
PDE4D Q08499 2/20 0.33
PDE3B Q13370 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18253640 0.92 MAPK10 (0.34) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL18253727 0.92 KDM4E (0.44) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL20060776 0.89 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL20060784 0.89 KDM4E (0.42) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL22596154 0.88 KDM4E (0.43) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL18253634 0.88 KDM4E (0.38) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL20060835 0.87 KDM4E (0.36) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL18254021 0.87 KDM4E (0.38) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL22596088 0.86 KDM4E (0.43) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL18253711 0.86 KDM4E (0.37) KDM4EATML3MBTL1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230272275-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-20230272275-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-20220135875-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2022-05-05 US disclosed
US-20210210699-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-07-08 US disclosed
US-20180105740-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2018-04-19 US disclosed
US-20180105740-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230272275-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PPA1, ENPP1, ITPA KDM4E 2389/4885ATM 4263/4885L3MBTL1 1249/4885
US-20220135875-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PPA1, ENPP1, ITPA KDM4E 2389/4885ATM 4263/4885L3MBTL1 1249/4885
US-20180105740-A1 PHOSPHOROUS HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PPA1, ENPP1, ITPA KDM4E 2389/4885ATM 4263/4885L3MBTL1 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.