Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068034 | 0.90 | PIK3CD (0.46) | PIK3CDPIK3CBPIK3CGPIK3CAMEN1 | |
| SCHEMBL28565071 | 0.83 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CGPIK3CAMETAP2 | |
| SCHEMBL20061345 | 0.83 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CGPIK3CAMETAP2 | |
| SCHEMBL20067857 | 0.79 | PIK3CD (0.58) | PIK3CDPIK3CBPIK3CGPIK3CAMEN1 | |
| SCHEMBL20081373 | 0.78 | FABP3 (0.44) | PIK3CDPIK3CBPIK3CGPIK3CAMEN1 | |
| SCHEMBL6121710 | 0.77 | PIK3CD (0.58) | PIK3CDPIK3CBPIK3CGPIK3CAMETAP2 | |
| SCHEMBL28567158 | 0.77 | PIK3CD (0.52) | PIK3CDPIK3CBPIK3CGPIK3CAMEN1 | |
| SCHEMBL20061346 | 0.75 | PIK3CD (0.50) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL28575779 | 0.75 | PIK3CD (0.50) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL20068033 | 0.75 | PIK3CD (0.50) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105527-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSTION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105527-A1 | HETEROARYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSTION FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH PI3 KINASES, CONTAINING SAME AS ACTIVE INGREDIENT | WEE2, WEE1, ITK | PIK3CD 14/4885PIK3CB 23/4885PIK3CG 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.