Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 19/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 18/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068033 | 1.00 | PIK3CD (0.50) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL20061346 | 1.00 | PIK3CD (0.50) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL28565071 | 0.79 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL20061345 | 0.79 | PIK3CD (0.53) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL20067857 | 0.75 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CACYP2D6 | |
| SCHEMBL20061344 | 0.75 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 | |
| SCHEMBL28565125 | 0.74 | PIK3CD (0.38) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL20061342 | 0.74 | PIK3CD (0.38) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL20068036 | 0.74 | PIK3CD (0.38) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL15226592 | 0.74 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107690433-B | Heteroaryl derivative or pharmaceutically acceptable salt thereof, preparation method thereof, and pharmaceutical composition for preventing or treating PI3 kinase-associated diseases comprising the same as active ingredient | 韩国化学研究院 | 2021-04-09 | — | — | CN | disclosed |