Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958671 | 0.86 | POLB (0.48) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL698233 | 0.84 | POLB (0.46) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL9861493 | 0.82 | POLB (0.45) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL5958703 | 0.82 | POLB (0.45) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL5958687 | 0.82 | POLB (0.45) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL11306411 | 0.82 | POLB (0.45) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL9154318 | 0.80 | POLB (0.52) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL698408 | 0.80 | POLB (0.52) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL532346 | 0.79 | POLB (0.56) | POLBALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL22927054 | 0.78 | PTPN5 (0.35) | POLBALDH1A1CYP3A4TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2535327-A1 | Insecticidal 3-acylaminobenzanilides | Bayer CropScience AG (DE) | 2012-12-19 | — | — | EP | disclosed |
| US-7964735-B2 | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2011-06-21 | — | — | US | disclosed |
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20090215623-A1 | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2009-08-27 | — | — | US | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| EP-1912933-A1 | INSECTICIDAL 3-ACYLAMINOBENZANILIDES | Bayer CropScience AG (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017075-A1 | INSECTICIDAL 3-ACYLAMINOBENZANILIDES | BAYER CROPSCIENCE AG (DE) | 2007-02-15 | — | — | WO | disclosed |
| EP-1006102-B1 | Process for the production of perfluoroalkylated aniline derivatives | NIHON NOHYAKU CO LTD (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6717013-B2 | EASILY ATTAINED WITH HIGH POSITIONAL SELECTIVITY AND YIELD; INTERMEDIATES AND RAW MATERIALS | NIHON NOHYAKU CO., LTD. (JP) | 2004-04-06 | — | — | US | disclosed |
| EP-1380568-A2 | Perfluoroalkylaniline derivatives | NIHON NOHYAKU CO., LTD. (JP) | 2004-01-14 | — | — | EP | disclosed |
| US-20030204104-A1 | Perfluoroalkylated aniline compound and process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 2003-10-30 | — | — | US | disclosed |
| US-6600074-B2 | Useful as intermediates or raw materials for the synthesis of agricultural chemicals, pharmaceuticals | NIHON NOHYAKU CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| US-20020198399-A1 | Perfluoroalkylated aniline compound and process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1006102-A2 | Aniline derivative and process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 2000-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | AADAC, HDHD5, HRH4 | POLB 4640/4885ALDH1A1 757/4885TDP1 4465/4885 |
| US-20090215623-A1 | Insecticidal 3-acylaminobenzanilides | CBR3, AADAC, DDT | POLB 4275/4885ALDH1A1 1739/4885TDP1 4540/4885 |
| US-20020198399-A1 | Perfluoroalkylated aniline compound and process for producing the same | CYP8B1, CCR8, AFF1 | POLB 2228/4885ALDH1A1 722/4885TDP1 2818/4885 |
| US-20030204104-A1 | Perfluoroalkylated aniline compound and process for producing the same | CYP8B1, CCR8, AFF1 | POLB 2228/4885ALDH1A1 722/4885TDP1 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.