SCHEMBL20061791

SCHEMBL20061791

c1ccc2cc3c(cc2c1)C1c2ccncc2C3c2ncncc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 1/20 0.37
MAPK10 P53779 1/20 0.37
KDM4E B2RXH2 4/20 0.36
EGFR P00533 1/20 0.35
CYP17A1 P05093 2/20 0.34
CYP19A1 P11511 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
NPC1 O15118 3/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 2/20 0.34
PKM P14618 1/20 0.34
RAB9A P51151 2/20 0.33
MAPT P10636 3/20 0.32
CYP2A6 P11509 1/20 0.32
PDPK1 O15530 1/20 0.32
MKNK2 Q9HBH9 1/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CA P42336 1/20 0.31
HTT P42858 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20061818 1.00 MAPK9 (0.37) MAPK9MAPK10KDM4EEGFRCYP17A1
SCHEMBL20061789 0.91 KDM4E (0.40) MAPK9MAPK10KDM4EEGFRCYP17A1
SCHEMBL20061807 0.89 CYP2A6 (0.33) EGFRCYP11B2ALDH1A1CYP2A6
SCHEMBL20061786 0.89 CYP2A6 (0.33) EGFRCYP11B2ALDH1A1CYP2A6
SCHEMBL20061821 0.86 KDM4E (0.31) KDM4EALDH1A1HTT
SCHEMBL20061820 0.86 EGFR (0.30) EGFR
SCHEMBL20061790 0.84 PDPK1 (0.35) MAPK9MAPK10KDM4ECYP17A1CYP19A1
SCHEMBL20061801 0.84 CYP17A1 (0.38) KDM4ECYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL20061806 0.84 KDM4E (0.37) MAPK9MAPK10KDM4EEGFRCYP17A1
SCHEMBL20061787 0.82 KDM4E (0.36) MAPK9MAPK10KDM4EEGFRCYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180108848-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180108848-A1 Organic electroluminescent materials and devices OSBP, OSBP2, OCIAD2 MAPK9 3258/4885MAPK10 2791/4885KDM4E 4668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.