Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 15/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | SCNN1B | P51168 | 1/20 | 0.52 |
| ▸ | SCNN1G | P51170 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17937122 | 0.93 | SCNN1A (0.52) | SCNN1ADRD5SCNN1BSCNN1GHRH3 | |
| SCHEMBL12635780 | 0.91 | SCNN1A (0.44) | SCNN1ADRD5SCNN1BSCNN1GHRH3 | |
| Iodide SCHEMBL2015067 | 0.90 | SCNN1A (0.43) | SCNN1ADRD5SCNN1BSCNN1GHRH3 | |
| SCHEMBL21335800 | 0.90 | SCNN1A (0.49) | SCNN1ADRD5SCNN1BSCNN1GHRH3 | |
| SCHEMBL18539755 | 0.90 | DRD5 (0.65) | SCNN1ADRD5SCNN1BSCNN1GHRH3 | |
| SCHEMBL16882078 | 0.89 | SCNN1A (0.52) | SCNN1ADRD5SCNN1BSCNN1GHRH3 | |
| SCHEMBL17937084 | 0.89 | SCNN1A (0.49) | SCNN1ADRD5SCNN1BSCNN1GHRH3 | |
| SCHEMBL17934216 | 0.87 | SCNN1A (0.46) | SCNN1ADRD5SCNN1BSCNN1GHRH3 | |
| SCHEMBL16882080 | 0.87 | SCNN1A (0.50) | SCNN1ADRD5SCNN1BSCNN1GHRH3 | |
| SCHEMBL16882075 | 0.87 | SCNN1A (0.50) | SCNN1ADRD5SCNN1BSCNN1GHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105512-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105512-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | TPSD1, TPSAB1, TMSB4X | SCNN1A 312/4885DRD5 3765/4885SCNN1B 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.