Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 19/20 | 0.55 |
| ▸ | PPARA | Q07869 | 17/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935920 | 0.86 | PPARG (0.71) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL8935911 | 0.86 | PPARG (0.71) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL2891961 | 0.85 | PPARG (0.67) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL7978358 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL421329 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL2560636 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL2901716 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL14122371 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL11550284 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2PPARGPPARA | |
| SCHEMBL17409391 | 0.82 | POLB (0.63) | SMN1; SMN2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088926-B2 | Substituted 2-methyl-2-phenoxy-N-propyl-propionamides as cannabinoid receptor antagonists/inverse agonists useful for treating obesity | JENRIN DISCOVERY, INC. (US) | 2012-01-03 | — | — | US | disclosed |