Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.71 |
| ▸ | PPARA | Q07869 | 17/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935911 | 1.00 | PPARG (0.71) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL2891961 | 0.88 | PPARG (0.67) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL28632391 | 0.86 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL200619 | 0.86 | SMN1; SMN2 (0.59) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL11550284 | 0.85 | SMN1; SMN2 (0.67) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL17409391 | 0.85 | POLB (0.63) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL2223492 | 0.84 | SMN1; SMN2 (0.57) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL433427 | 0.84 | SMN1; SMN2 (0.65) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL1745447 | 0.84 | PPARG (0.66) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL8935859 | 0.84 | SMN1; SMN2 (0.70) | PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |