SCHEMBL20062322

SCHEMBL20062322

c1ccc(-n2c3ccccc3n(-c3ccccc3)c3cc4c(cc32)c2ccc(-c3cccc5c3sc3ccccc35)cc2c2cc3c(cc2c2ncc(-c5cccc6c5sc5ccccc56)cc42)n(-c2ccccc2)c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
PRKDC P78527 3/20 0.37
DNPH1 O43598 1/20 0.34
LIMK1 P53667 5/20 0.31
PARP14 Q460N5 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062312 1.00 ALOX5 (0.44) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL20062311 0.91 ALOX5 (0.43) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL20062212 0.91 ALOX5 (0.43) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL20062216 0.91 ALOX5 (0.43) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL20062217 0.91 ALOX5 (0.43) ALOX5PRKDCDNPH1LIMK1PARP14
SCHEMBL20062272 0.91 ALOX5 (0.52) ALOX5PRKDCDNPH1PARP14KDM4E
SCHEMBL20062141 0.91 ALOX5 (0.52) ALOX5PRKDCDNPH1PARP14KDM4E
SCHEMBL20062267 0.91 ALOX5 (0.52) ALOX5PRKDCDNPH1PARP14KDM4E
SCHEMBL20062269 0.91 ALOX5 (0.52) ALOX5PRKDCDNPH1PARP14KDM4E
SCHEMBL20062149 0.91 ALOX5 (0.52) ALOX5PRKDCDNPH1PARP14KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10608185-B2 Organic electroluminescent materials and devices UNIVERAL DISPLAY CORPORATION (US) 2020-03-31 US disclosed
US-20180108844-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-04-19 US disclosed
US-20180108844-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180108844-A1 Organic Electroluminescent Materials and Devices SLCO4C1, SLCO2A1, SLCO2B1 ALOX5 1559/4885PRKDC 4622/4885DNPH1 2511/4885
US-10608185-B2 Organic electroluminescent materials and devices SLCO4C1, SLCO2A1, SLCO2B1 ALOX5 1559/4885PRKDC 4622/4885DNPH1 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.