SCHEMBL20062957

SCHEMBL20062957

Cc1ccc(N2/C(=C3/N(c4ccc(C)o4)c4ccc(C(C)(C)C)cc4N3c3ccc(C)o3)N(c3ccc(C)o3)c3cc(C(C)(C)C)ccc32)o1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062958 0.79 PRKDC (0.34) HPGD
SCHEMBL20071964 0.78 MAPT (0.31) TDP1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL18905684 0.73 CA9 (0.39) TDP1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL18905679 0.73 CA9 (0.39) TDP1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL20062954 0.72 TRPV1 (0.31) TSHR
SCHEMBL18905704 0.71 ALDH1A1 (0.35) TDP1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL18905695 0.71 ALDH1A1 (0.32) TDP1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL18905680 0.70 TSHR (0.38) TDP1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL18905685 0.70 KCNH2 (0.36) TDP1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL18905689 0.70 TSHR (0.38) TDP1ALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 TDP1 2316/4885ALDH1A1 395/4885HPGD 3728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.