Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPA | P38571 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924465 | 1.00 | LIPA (0.32) | LIPA | |
| SCHEMBL22624243 | 0.90 | LIPA (0.36) | LIPA | |
| SCHEMBL10234936 | 0.90 | LIPA (0.36) | LIPA | |
| SCHEMBL9924468 | 0.81 | LIPA (0.32) | LIPA | |
| SCHEMBL8487570 | 0.81 | LIPA (0.32) | LIPA | |
| SCHEMBL8488751 | 0.81 | LIPA (0.32) | LIPA | |
| SCHEMBL15132663 | 0.81 | LIPA (0.32) | LIPA | |
| SCHEMBL20064013 | 0.79 | LIPA (0.32) | LIPA | |
| SCHEMBL8484362 | 0.79 | LIPA (0.32) | LIPA | |
| SCHEMBL3414815 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |