Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011306 | 0.73 | MAP4K4 (0.36) | MAPK8MERTK | |
| SCHEMBL5549154 | 0.70 | GRIN2B (0.42) | MERTK | |
| SCHEMBL5549157 | 0.70 | GRIN2B (0.42) | MERTK | |
| SCHEMBL5543259 | 0.70 | GRIN2B (0.42) | MERTK | |
| SCHEMBL5543254 | 0.70 | GRIN2B (0.42) | MERTK | |
| SCHEMBL5545337 | 0.70 | CRBN (0.41) | CPB1CPB2 | |
| SCHEMBL5545416 | 0.69 | CRBN (0.46) | — | |
| SCHEMBL17592449 | 0.69 | HRH1 (0.42) | — | |
| SCHEMBL27394629 | 0.66 | IDO1 (0.43) | — | |
| SCHEMBL1220398 | 0.65 | MAP4K4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |