⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006115 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL1060663 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL2384813 | 0.68 | TSHR (0.39) | — | |
| SCHEMBL25408699 | 0.64 | — | — | |
| SCHEMBL9436377 | 0.64 | TSHR (0.35) | — | |
| SCHEMBL78637 | 0.64 | TSHR (0.35) | — | |
| SCHEMBL2384817 | 0.64 | — | — | |
| SCHEMBL10632508 | 0.64 | — | — | |
| SCHEMBL887785 | 0.64 | TSHR (0.30) | — | |
| SCHEMBL1061644 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4756863-B2 | — | — | 2011-08-24 | — | — | JP | claimed |
| US-7247720-B2 | Phosphitylation process | AVECIA BIOTECHNOLOGY INC. (US) | 2007-07-24 | — | — | US | claimed |
| EP-1554300-B1 | PHOSPHITYLATION PROCESS | AVECIA BIOTECHNOLOGY INC (US) | 2007-05-23 | — | — | EP | claimed |
| US-20060069247-A1 | Phosphitylation process | AVECIA BIOTECHNOLOGY INC. (US) | 2006-03-30 | — | — | US | claimed |
| EP-1554300-A1 | PHOSPHITYLATION PROCESS | Avecia Biotechnology, Inc. (US) | 2005-07-20 | — | — | EP | claimed |
| WO-2004035599-A1 | PHOSPHITYLATION PROCESS | AVECIA BIOTECHNOLOGY INC. (US) | 2004-04-29 | — | — | WO | claimed |
| EP-1590361-B1 | PROCESS FOR PURIFYING OLIGONUCLEOTIDE SYNTHONS | NITTO DENKO AVECIA INC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-7960542-B2 | Process for purifying oligonucleotide synthons | AVECIA BIOTECHNOLOGY, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-7560555-B2 | Process for the preparation of phosphitylation agents | AVECIA BIOTECHNOLOGY INC. (US) | 2009-07-14 | — | — | US | disclosed |
| US-7247720-B2 | Phosphitylation process | AVECIA BIOTECHNOLOGY INC. (US) | 2007-07-24 | — | — | US | disclosed |
| EP-1554300-B1 | PHOSPHITYLATION PROCESS | AVECIA BIOTECHNOLOGY INC (US) | 2007-05-23 | — | — | EP | disclosed |
| US-20060173187-A1 | Process for the preparation of phosphitylation agents | NITTO DENKO AVECIA, INC. | 2006-08-03 | — | — | US | disclosed |
| US-20060135760-A1 | Process for purifying oligonucleotide synthons | NITTO DENKO AVECIA, INC. | 2006-06-22 | — | — | US | disclosed |
| US-20060069247-A1 | Phosphitylation process | AVECIA BIOTECHNOLOGY INC. (US) | 2006-03-30 | — | — | US | disclosed |
| EP-1590361-A2 | PROCESS FOR PURIFYING OLIGONUCLEOTIDE SYNTHONS | Avecia Limited (GB) | 2005-11-02 | — | — | EP | disclosed |
| EP-1554300-A1 | PHOSPHITYLATION PROCESS | Avecia Biotechnology, Inc. (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004055037-A2 | PROCESS FOR PURIFYING OLIGONUCLEOTIDE SYNTHONS | AVECIA LIMITED (GB) | 2004-07-01 | — | — | WO | disclosed |
| WO-2004035599-A1 | PHOSPHITYLATION PROCESS | AVECIA BIOTECHNOLOGY INC. (US) | 2004-04-29 | — | — | WO | disclosed |