SCHEMBL78637

SCHEMBL78637

CC(C#N)OP(N)OC(C)C#N

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9436377 1.00 TSHR (0.35) TSHR
SCHEMBL442364 0.80
SCHEMBL6036511 0.79
SCHEMBL2384813 0.77 TSHR (0.39) TSHR
SCHEMBL3638619 0.74 TSHR (0.32) TSHR
SCHEMBL2384817 0.72
SCHEMBL10632508 0.72
SCHEMBL1060663 0.72 TSHR (0.30) TSHR
SCHEMBL6325646 0.70 TSHR (0.33) TSHR
SCHEMBL2006115 0.69 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3079 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116212906-B Phosphorylated immobilized binary catalyst, preparation method and application thereof 中国人民解放军军事科学院系统工程研究院 2023-12-22 CN claimed
CN-116903690-A Nucleoside dimer, preparation method thereof and application thereof in DNA synthesis 中国人民解放军军事科学院军事医学研究院 2023-10-20 CN claimed
CN-116212906-A Phosphorylated immobilized binary catalyst, preparation method and application thereof 中国人民解放军军事科学院系统工程研究院 2023-06-06 CN claimed
CN-105705638-B What is improved has dynamical nanoparticle form oligonucleotide structure and preparation method thereof 柏业公司 2019-11-26 CN claimed
EP-0613502-B1 Methods and reagents for detection of bacteria in cerebrospinal fluid HOFFMANN LA ROCHE (CH) 1998-10-21 EP claimed
US-5738829-A Recovery of oligonucleotides by gas phase cleavage BARRSKOGEN, INC. (US) 1998-04-14 US claimed
US-5514789-A Recovery of oligonucleotides by gas phase cleavage BARRSKOGEN, INC. (US) 1996-05-07 US claimed
CN-122094704-A Formulations for oral administration of active agents comprising a combination of acid-neutralizing polymer and non-polymeric material 2026-05-26 CN disclosed
US-12637672-B2 Oligonucleotide compositions and methods thereof WAVE LIFE SCIENCES LTD. (SG) 2026-05-26 US disclosed
WO-2026105126-A1 DNA-BASED MECHANOSENSITIVE DELIVERY AGENTS AND USES THEREOF TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2026-05-21 WO disclosed
US-12624391-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2026-05-12 US disclosed
US-20260124233-A1 COMPOSITIONS FOR AQUACULTURING VIAQUA THERAPEUTICS LTD. (IL) 2026-05-07 US disclosed
US-20260117244-A1 INHIBITORY RNA FOR THE CONTROL OF PHYTOPATHOGENS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-30 US disclosed
WO-1989005358-A1 DNA AND RNA MOLECULES STABILIZED BY MODIFICATIONS OF THE 3'-TERMINAL PHOSPHODIESTER LINKAGE AND THEIR USE AS NUCLEIC ACID PROBES AND AS THERAPEUTIC AGENTS TO BLOCK THE EXPRESSION OF SPECIFICALLY TARGETED GENES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1989-06-15 WO disclosed
WO-1989004375-A1 LANTHANIDE CHELATE-TAGGED NUCLEIC ACID PROBES SISKA DIAGNOSTICS, INC. (US) 1989-05-18 WO disclosed
WO-1989003222-A1 SOLUBLE HUMAN CD4 FRAGMENTS AND USES THEREFOR DANA-FABER CANCER INSTITUTE (US) 1989-04-20 WO disclosed
EP-0276302-A1 NUCLEIC ACID PROBE ASSAY METHODS AND COMPOSITIONS. SISKA DIAGNOSTICS INC (US) 1988-08-03 EP disclosed
EP-0273040-A1 BIOLOGICAL CONTAINMENT. GENEXPRESS APS (DK) 1988-07-06 EP disclosed
WO-1988001302-A1 NUCLEIC ACID PROBE ASSAY METHODS AND COMPOSITIONS SISKA DIAGNOSTICS, INC. (US) 1988-02-25 WO disclosed
WO-1987005932-A1 BIOLOGICAL CONTAINMENT GENEXPRESS APS (DK) 1987-10-08 WO disclosed