Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789675 | 1.00 | SLC6A2 (0.51) | SLC6A2SLC6A4YTHDC1KMT2AMEN1 | |
| SCHEMBL3376962 | 0.90 | YTHDC1 (0.58) | SLC6A2SLC6A4YTHDC1KMT2AMEN1 | |
| SCHEMBL14795012 | 0.89 | YTHDC1 (0.46) | SLC6A2SLC6A4YTHDC1KMT2AMEN1 | |
| SCHEMBL23583787 | 0.89 | YTHDC1 (0.46) | SLC6A2SLC6A4YTHDC1KMT2AMEN1 | |
| SCHEMBL14506424 | 0.87 | KMT2A (0.47) | SLC6A2SLC6A4YTHDC1KMT2AMEN1 | |
| SCHEMBL13017781 | 0.84 | SLC6A2 (0.53) | SLC6A2SLC6A4YTHDC1KMT2AMEN1 | |
| SCHEMBL14506713 | 0.83 | GRIN2B (0.55) | GRIN2BACHEALDH1A1TSHRKDM4E | |
| SCHEMBL12680890 | 0.83 | GRIN2B (0.55) | GRIN2BACHEALDH1A1TSHRKDM4E | |
| SCHEMBL13744978 | 0.83 | GRIN2B (0.55) | GRIN2BACHEALDH1A1TSHRKDM4E | |
| SCHEMBL3371525 | 0.82 | GRIN2B (0.63) | SLC6A2SLC6A4YTHDC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |