Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30959818 | 1.00 | ESR1 (0.45) | ESR1ESR2APOBEC3GPDCD1CD274 | |
| SCHEMBL2009165 | 0.85 | APOBEC3G (0.37) | ESR1ESR2APOBEC3GPDCD1CD274 | |
| SCHEMBL18796263 | 0.85 | SLC6A4 (0.39) | ESR1ESR2APOBEC3GPDCD1CD274 | |
| SCHEMBL29127795 | 0.81 | ALDH1A1 (0.35) | ESR1ESR2APOBEC3GALDH1A1KDM4E | |
| SCHEMBL21195924 | 0.80 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL20551650 | 0.80 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3ALDH1A1 | |
| SCHEMBL9206225 | 0.79 | APOBEC3G (0.48) | APOBEC3GPDCD1CD274TSHRNOTUM | |
| SCHEMBL2002146 | 0.78 | APOBEC3G (0.41) | APOBEC3GPDCD1CD274TSHRNOTUM | |
| SCHEMBL13924104 | 0.78 | HTR2A (0.41) | ESR1ESR2HPGDTSHRNPC1 | |
| SCHEMBL12191049 | 0.78 | ESR1 (0.54) | ESR1ESR2NR1H2NR1H3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165552-A | Slag-hanging-preventing high-temperature-resistant coating and preparation process thereof | 包头市龙道然环保科技发展有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-118165552-A | Slag-hanging-preventing high-temperature-resistant coating and preparation process thereof | 包头市龙道然环保科技发展有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-118165552-A | Slag-hanging-preventing high-temperature-resistant coating and preparation process thereof | 包头市龙道然环保科技发展有限公司 | 2024-06-11 | — | — | CN | disclosed |
| US-7960571-B2 | Silicon-based cross-coupling reagent and production method of organic compound using the same | KYOTO UNIVERSITY (JP) | 2011-06-14 | — | — | US | disclosed |
| US-7960571-B2 | Silicon-based cross-coupling reagent and production method of organic compound using the same | KYOTO UNIVERSITY (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | KYOTO UNIVERSITY (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | KYOTO UNIVERSITY (JP) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069577-A1 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same | DNMT1, TET3, CTCF | ESR1 557/4885ESR2 1692/4885APOBEC3G 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.