Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185252 | 0.77 | SMN1; SMN2 (0.34) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL10770944 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL894405 | 0.74 | CTSA (0.37) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL30301185 | 0.73 | ALDH1A1 (0.38) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL20027998 | 0.73 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL12372972 | 0.73 | TSHR (0.53) | ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL4990894 | 0.72 | TSHR (0.46) | ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL18805347 | 0.69 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL4432272 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL4990902 | 0.68 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105553-A1 | POLYPEPTIDES, PEPTIDES, AND PROTEINS FUNCTIONALIZED BY ALKYLATION OF THIOETHER GROUPS VIA RING-OPENING REACTIONS | NATIONAL SCIENCE FOUNDATION | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105553-A1 | POLYPEPTIDES, PEPTIDES, AND PROTEINS FUNCTIONALIZED BY ALKYLATION OF THIOETHER GROUPS VIA RING-OPENING REACTIONS | PTMS, TMT1A, PTMA | CTSA 2443/4885ACHE 2997/4885ALDH1A1 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.