SCHEMBL20066899

SCHEMBL20066899

CC1(C2(C)c3cc(N(c4ccc(F)cc4)c4ccc(F)cc4)ccc3-c3ccc(N(c4ccc(F)cc4)c4ccc(F)cc4)cc32)c2cc(N(c3ccc(F)cc3)c3ccc(F)cc3)ccc2-c2ccc(N(c3ccc(F)cc3)c3ccc(F)cc3)cc21

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.34
APP P05067 1/20 0.32
AKR1A1 P14550 1/20 0.31
AKR1B1 P15121 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
PDGFRB P09619 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20066650 0.92 PDK2 (0.42) PDK2
SCHEMBL13222545 0.89 PDK2 (0.34) PDK2APPAKR1A1AKR1B1KDM4E
SCHEMBL12120373 0.86 PDK2 (0.33) PDK2APP
SCHEMBL20100715 0.85 PDK2 (0.33) PDK2APPAKR1A1AKR1B1
SCHEMBL20066887 0.83 PDK2 (0.42) PDK2APPKDM4EALDH1A1MAPT
SCHEMBL13222546 0.83 ACHE (0.42) PDK2ALDH1A1
SCHEMBL14491212 0.83 PDK2 (0.40) PDK2KDM4EALDH1A1MAPTMAPK1
SCHEMBL18052475 0.82 PDK2 (0.42) PDK2
SCHEMBL20066900 0.81 PDK2 (0.35) PDK2APP
SCHEMBL16621775 0.80 ACHE (0.39) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10907093-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-02 US disclosed
US-20180105741-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-19 US disclosed
US-20180105741-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180105741-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME C1S, SCO2, CCND2 PDK2 1507/4885APP 2012/4885AKR1A1 1937/4885
US-10907093-B2 Condensed cyclic compound and organic light-emitting device including the same C1S, SCO2, CCND2 PDK2 1507/4885APP 2012/4885AKR1A1 1937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.