Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973703 | 0.95 | HSD11B1 (0.71) | HSD11B1IDH1 | |
| SCHEMBL13271633 | 0.95 | HSD11B1 (0.71) | HSD11B1IDH1 | |
| SCHEMBL13271401 | 0.92 | IDH1 (0.72) | HSD11B1IDH1 | |
| SCHEMBL2008483 | 0.92 | IDH1 (0.72) | HSD11B1IDH1 | |
| SCHEMBL2008002 | 0.87 | IDH1 (0.72) | HSD11B1IDH1 | |
| SCHEMBL2008000 | 0.87 | IDH1 (0.72) | HSD11B1IDH1 | |
| SCHEMBL4557637 | 0.87 | IDH1 (0.72) | HSD11B1IDH1 | |
| SCHEMBL3402501 | 0.87 | HSD11B1 (0.74) | HSD11B1IDH1 | |
| SCHEMBL3402508 | 0.87 | HSD11B1 (0.74) | HSD11B1IDH1 | |
| SCHEMBL2006743 | 0.86 | HSD11B1 (0.49) | HSD11B1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086939-B8 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2011-06-22 | — | — | EP | claimed |