Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 3/20 | 0.57 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.57 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.57 |
| ▸ | MERTK | Q12866 | 14/20 | 0.56 |
| ▸ | AXL | P30530 | 13/20 | 0.56 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.50 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20067752 | 0.92 | BMPR1B (0.58) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20067672 | 0.91 | BMPR1B (0.57) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21460284 | 0.91 | BMPR1B (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL20067644 | 0.91 | BMPR1B (0.61) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21460287 | 0.88 | BMPR1B (0.56) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21460213 | 0.88 | AXL (0.60) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21460290 | 0.87 | BMPR1B (0.57) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21460279 | 0.87 | BMPR1B (0.63) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21473934 | 0.87 | BMPR1B (0.53) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL21473948 | 0.87 | IKBKE (0.54) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523292-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2021-12-15 | — | — | EP | disclosed |
| WO-2018071343-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2018-04-19 | — | — | WO | disclosed |