Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 8/20 | 0.69 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068017 | 0.89 | ACMSD (0.68) | ACMSDKMT2AALDH1A1NFE2L2POLB | |
| SCHEMBL20137895 | 0.89 | ACMSD (0.68) | ACMSDKMT2AALDH1A1NFE2L2POLB | |
| SCHEMBL29528679 | 0.89 | ACMSD (0.67) | ACMSDKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL20068151 | 0.89 | ACMSD (0.67) | ACMSDKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL20068211 | 0.88 | ACMSD (0.69) | ACMSDKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29529176 | 0.88 | ACMSD (0.84) | ACMSDKMT2AHPGDNFE2L2POLB | |
| SCHEMBL20137807 | 0.88 | ACMSD (0.84) | ACMSDKMT2AHPGDNFE2L2POLB | |
| SCHEMBL20068050 | 0.88 | ACMSD (0.84) | ACMSDKMT2AHPGDNFE2L2POLB | |
| SCHEMBL23696631 | 0.88 | ACMSD (0.70) | ACMSDKMT2AKDM4EALDH1A1NFE2L2 | |
| SCHEMBL20068065 | 0.87 | ACMSD (0.70) | ACMSDKMT2AALDH1A1NFE2L2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069532-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2018-04-19 | — | — | WO | disclosed |