Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.57 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554736 | 0.85 | PTGDR2 (0.62) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL15330537 | 0.84 | SRC (0.55) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL2557069 | 0.82 | SRC (0.54) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL2556100 | 0.82 | SRC (0.54) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL2555240 | 0.81 | SRC (0.56) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL20150988 | 0.81 | SRC (0.56) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL1125257 | 0.81 | SRC (0.58) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL4598936 | 0.81 | TLR2 (0.55) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL74619 | 0.80 | ALDH1A1 (0.65) | TLR2ERN1TLR1TLR6SRC | |
| SCHEMBL7357540 | 0.80 | NPC1 (0.59) | TLR2ERN1TLR1TLR6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069532-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2018-04-19 | — | — | WO | disclosed |