SCHEMBL20068641

SCHEMBL20068641

Brc1ccc2cc3c4cccc5c6ccccc6n(c3cc2c1)c54

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.43
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
MAPT P10636 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
HTT P42858 2/20 0.36
POLB P06746 1/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
FTO Q9C0B1 1/20 0.36
TSPO P30536 3/20 0.34
RAD52 P43351 1/20 0.33
ACHE P22303 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
AURKA O14965 1/20 0.32
TP53 P04637 1/20 0.31
CDK4 P11802 1/20 0.30
CCND1 P24385 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20068467 1.00 CYP2A6 (0.43) CYP2A6MEN1KMT2AMAPTKDM4E
SCHEMBL20857811 0.87 KDM4E (0.44) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL19564398 0.85 KDM4E (0.42) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL20068683 0.85 ESR2 (0.36) CYP2A6MEN1KMT2AMAPTKDM4E
SCHEMBL20068464 0.84 ESR2 (0.38) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL24735191 0.84 KDM4E (0.41) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL29649844 0.84 TSPO (0.44) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL15453212 0.84 TSPO (0.44) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL868330 0.84 MEN1 (0.41) CYP2A6MEN1KMT2AMAPTKDM4E
SCHEMBL29783004 0.84 MEN1 (0.41) CYP2A6MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018070824-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2018-04-19 WO disclosed