Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 8/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8302494 | 0.92 | NAAA (0.55) | CHRM2CHRM1NAAAEPHX2 | |
| SCHEMBL20147457 | 0.82 | NAAA (0.49) | CHRM2CHRM1NAAAEPHX2 | |
| SCHEMBL20152050 | 0.82 | CHRM2 (0.48) | CHRM2CHRM1NAAAEPHX2 | |
| SCHEMBL21664720 | 0.81 | CHRM2 (0.44) | CHRM2CHRM1NAAAEPHX2 | |
| SCHEMBL10672205 | 0.79 | NAAA (0.52) | CHRM2CHRM1NAAAEPHX2 | |
| SCHEMBL25910599 | 0.79 | CHRM2 (0.51) | CHRM2CHRM1NAAAEPHX2 | |
| SCHEMBL20147426 | 0.78 | NAAA (0.52) | CHRM2CHRM1NAAAEPHX2 | |
| SCHEMBL21004227 | 0.78 | NAAA (0.54) | CHRM2CHRM1NAAAEPHX2 | |
| SCHEMBL20137677 | 0.78 | EPHX2 (0.55) | CHRM2CHRM1NAAAEPHX2 | |
| SCHEMBL20137678 | 0.78 | EPHX2 (0.55) | CHRM2CHRM1NAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071454-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |