Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22857085 | 0.87 | RET (0.44) | RETADAM17 | |
| SCHEMBL20152059 | 0.86 | RET (0.42) | RET | |
| SCHEMBL20069525 | 0.76 | RET (0.41) | RETADAM17 | |
| SCHEMBL20069719 | 0.75 | RET (0.41) | RETADAM17 | |
| SCHEMBL20158431 | 0.71 | RET (0.39) | RET | |
| SCHEMBL20069723 | 0.71 | RET (0.42) | RET | |
| SCHEMBL20069713 | 0.71 | RET (0.42) | RET | |
| SCHEMBL20069711 | 0.70 | RET (0.40) | RET | |
| SCHEMBL20148067 | 0.70 | RET (0.40) | RET | |
| SCHEMBL20068870 | 0.70 | RET (0.40) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071454-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |