Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20069842 | 0.79 | RET (0.34) | RET | |
| SCHEMBL23707157 | 0.77 | — | — | |
| SCHEMBL21652019 | 0.75 | RET (0.30) | RET | |
| SCHEMBL20148066 | 0.71 | RET (0.33) | RET | |
| SCHEMBL19798422 | 0.69 | FDFT1 (0.39) | — | |
| SCHEMBL24200792 | 0.66 | NPC1 (0.33) | — | |
| SCHEMBL22360699 | 0.63 | GBA1 (0.34) | — | |
| SCHEMBL24912290 | 0.62 | PIK3CD (0.31) | — | |
| SCHEMBL26528093 | 0.59 | GBA1 (0.32) | — | |
| SCHEMBL24773525 | 0.58 | HRH4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071454-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |