Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13803188 | 0.79 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL23588937 | 0.79 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL21039454 | 0.74 | ATM (0.31) | PIK3CD | |
| SCHEMBL24359072 | 0.74 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL3436793 | 0.73 | — | — | |
| SCHEMBL18462940 | 0.71 | GBA1 (0.32) | — | |
| SCHEMBL26130940 | 0.71 | PDE7A (0.34) | — | |
| Hydrochloric Acid SCHEMBL4349290 | 0.71 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL3436790 | 0.71 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL18878200 | 0.70 | ACHE (0.37) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601297-B9 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC (US) | 2023-05-24 | — | — | EP | disclosed |